Does it really matter if I use an NVME SSD GEN 3 or GEN 4?

Does it really matter if I use an NVME SSD GEN 3 or GEN 4? can i put a gen 4 m 2 in a gen 3 slot
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canada green card lottery free registration 2 x16 Gen 4 Card is compatible with the Intel® X299, Z390, Z370 and future platforms' RAID-on-CPU function, and supports PCIe NVMe RAID on the AMD TRX40 and

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