HD Native card in PCIe x1 slot?

pcie x1 in x16 slot
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Riser PCIE x1 to x16 GPU performance loss test in any games, compared with PCIE x16 from

Yes it can be done, provided that motherboard manufacturers provide a space between the slots big enough for your x16 expansion card to fit

pcie 40 in 30 slot PCIe x1 slots are often used for less demanding expansion cards, such as PCIe x16: This is the largest PCIe slot with 16 data lanes PCIe x16 slots

pcie 4 ssd in pcie 3 slot PCIe x1 slots are often used for less demanding expansion cards, such as PCIe x16: This is the largest PCIe slot with 16 data lanes PCIe x16 slots